News

SENOMYX, INC. TO WEBCAST FINANCIAL RESULTS FOR FOURTH QUARTER AND FISCAL YEAR ENDING DECEMBER 31, 2004 CONFERENCE CALL

LA JOLLA, CA, February 3, 2005 - Senomyx, Inc. (NASDAQ: SNMX) will release its fourth quarter and year-end 2004 financial results on Thursday, February 10, 2005 before the opening of the U.S. financial markets. The Company will also host a conference call and live audio webcast at 11:00 a.m. Eastern Time (8:00 a.m. Pacific Time) that same day. During the call, Senomyx's management will discuss the financial results for the fourth quarter and year-end 2004 and financial guidance for 2005.

To participate in the live conference call, U.S. residents should dial (877) 407-8299, and international callers should dial (201) 689-8341. The participant passcode for this conference call is 00137628.

The conference call is also being webcast live over the Internet on Senomyx's website (www.senomyx.com) under the investor relations section and will be archived there for 30 days following the conclusion of the call. Please connect to Senomyx's website several minutes prior to the start of the conference call to ensure adequate time for any software download that may be necessary.

About Senomyx, Inc. (www.senomyx.com)

Senomyx is a biotechnology company using proprietary taste receptor-based assays, screening technologies and optimization chemistry to discover and develop novel flavor enhancers and taste modulators for the packaged food and beverage industry. Senomyx has entered into product discovery and development collaborations with four of the world's leading packaged food and beverage companies: Campbell Soup Company, The Coca-Cola Company, Kraft Foods Global, Inc. and Nestlé SA. Senomyx's current programs focus on the development of flavor enhancers and taste modulators in taste areas including savory, sweet, salt and bitter.

Contacts

Finance		Investor Relations
John Poyhonen		Susan Neath
Vice President, CFO and CBO		Atkins + Associates
Senomyx, Inc.		858-527-3486
858-646-8302