News

SENOMYX TO WEBCAST CORPORATE PRESENTATION AT THE FOURTH ANNUAL NEEDHAM BIOTECHNOLOGY CONFERENCE

LA JOLLA, CA - May 19, 2005 - Senomyx, Inc. (NASDAQ: SNMX) announced today that the Company's President and CEO, Kent Snyder, will present a corporate overview on Thursday, May 26, 2005 at 1:30 p.m. Eastern Time (10:30 a.m. Pacific Time) during the Fourth Annual Needham Biotechnology Conference. The conference is taking place at The New York Palace Hotel. During his presentation, Mr. Snyder will provide an overview of the Company's pipeline of novel flavors, flavor enhancers and taste modulators and a product development update.

To access the live presentation or a subsequent archived recording please log onto Senomyx's website at http://www.senomyx.com and click on the "Investor Relations" tab. The archived webcast will be available for 30 days following the presentation. Please connect to Senomyx's website prior to the start of the webcast to ensure adequate time to download any software that may be necessary.

About Senomyx, Inc. (www.senomyx.com)

Senomyx is a biotechnology company using proprietary taste receptor-based assays, screening technologies and optimization chemistry to discover and develop novel flavors, flavor enhancers and taste modulators for the packaged food and beverage industry. Senomyx's current programs focus on the development of flavors, flavor enhancers and taste modulators in the savory, sweet, salt and bitter taste areas. Senomyx has entered into product discovery and development collaborations with four of the world's leading packaged food and beverage companies: Campbell Soup Company, The Coca-Cola Company, Kraft Foods Global, Inc. and Nestlé SA.

Contacts

Corporate:		Investor Relations
Kent Snyder		Susan Neath
President & CEO		Atkins + Associates
Senomyx, Inc.		Media & Investor Relations
858-646-8300		858-527-3486