News

SENOMYX TO WEBCAST CORPORATE PRESENTATION AT THE SIXTH ANNUAL NEEDHAM & COMPANY BIOTECH & MEDTECH CONFERENCE

SAN DIEGO, CA - June 6, 2007 - Senomyx, Inc. (NASDAQ: SNMX), a leading company focused on using proprietary technologies to discover and develop novel flavor ingredients for the packaged food and beverage industry, announced today that the Company's Chief Financial & Business Officer, John Poyhonen, and its Chief Scientific Officer and Executive Vice President, Mark Zoller, Ph.D., will present a corporate overview on Wednesday, June 13, at 1:30 p.m. Eastern Time (10:30 a.m. Pacific Time) during the Sixth Annual Needham & Company Biotech & Medtech Conference. The conference is taking place at the New York Palace Hotel in New York City. The presentation will provide a summary of the Company's pipeline of novel flavors, flavor enhancers and taste modulators.

To access the live presentation or a subsequent archived recording, please log onto Senomyx's website at http://www.senomyx.com and click on the "Investor Relations" tab. The archived webcast will be available for 30 days following the presentation. Please connect to Senomyx's website prior to the start of the webcast to ensure adequate time to download any software that may be necessary.

About Senomyx, Inc. (www.senomyx.com) Senomyx is a leading company using proprietary taste receptor-based assays, screening technologies and optimization chemistry to discover and develop novel flavors, flavor enhancers and taste modulators for the packaged food and beverage industry. The Company is focusing on the development of these flavor ingredients in the savory, sweet, salt and bitter areas. Senomyx has entered into product discovery and development collaborations with seven of the world's leading packaged food and beverage companies: Ajinomoto Co., Inc., Cadbury Schweppes, Campbell Soup Company, The Coca-Cola Company, Kraft Foods Global, Inc., Nestlé SA, and Solae, LLC. Nestlé is currently marketing products that contain one of Senomyx's flavor ingredients. For more information, please visit www.senomyx.com.

Contacts

Investor Relations:

Gwen Rosenberg

Vice President, Investor Relations & Corporate Communications

Senomyx, Inc.

858-646-8369

gwen.rosenberg@senomyx.com